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Noradrenergic ‘Tone’ Determines Dichotomous Control of Cortical Spike-Timing-Dependent Plasticity

Norepinephrine (NE) is widely distributed throughout the brain. It modulates intrinsic currents, as well as amplitude and frequency of synaptic transmission affecting the ‘signal-to-noise ratio’ of sensory responses. In the visual cortex, α(1)- and β-adrenergic receptors (AR) gate opposing effects o...

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Detalles Bibliográficos
Autores principales: Salgado, Humberto, Köhr, Georg, Treviño, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358707/
https://www.ncbi.nlm.nih.gov/pubmed/22639725
http://dx.doi.org/10.1038/srep00417