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Diversity-Oriented Synthesis Approach to Macrocycles via Oxidative Ring Expansion

Macrocycles are key structural elements in numerous bioactive small molecules and are attractive targets in the diversity-oriented synthesis of natural product-based libraries. However, efficient and systematic access to diverse collections of macrocycles has proven difficult using classical macrocy...

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Detalles Bibliográficos
Autores principales: Kopp, Felix, Stratton, Christopher F., Akella, Lakshmi B., Tan, Derek S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359144/
https://www.ncbi.nlm.nih.gov/pubmed/22406518
http://dx.doi.org/10.1038/nchembio.911