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Nurr1 regulates Top IIβ and functions in axon genesis of mesencephalic dopaminergic neurons
BACKGROUND: NURR1 (also named as NR4A2) is a member of the steroid/thyroid hormone receptor family, which can bind to DNA and modulate expression of target genes. Previous studies have shown that NURR1 is essential for the nigral dopaminergic neuron phenotype and function maintenance, and the defect...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359158/ https://www.ncbi.nlm.nih.gov/pubmed/22296971 http://dx.doi.org/10.1186/1750-1326-7-4 |