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Nurr1 regulates Top IIβ and functions in axon genesis of mesencephalic dopaminergic neurons

BACKGROUND: NURR1 (also named as NR4A2) is a member of the steroid/thyroid hormone receptor family, which can bind to DNA and modulate expression of target genes. Previous studies have shown that NURR1 is essential for the nigral dopaminergic neuron phenotype and function maintenance, and the defect...

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Detalles Bibliográficos
Autores principales: Heng, Xin, Jin, Gang, Zhang, Xin, Yang, Dehuang, Zhu, Mingzhe, Fu, Shijun, Li, Xuping, Le, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359158/
https://www.ncbi.nlm.nih.gov/pubmed/22296971
http://dx.doi.org/10.1186/1750-1326-7-4

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