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Histone deacetylase activity is decreased in peripheral blood monocytes in patients with COPD
BACKGROUND: Histone deacetylase (HDAC) is an enzyme that regulates chromatin structure and inflammatory gene expression. In patients with chronic obstructive pulmonary disease (COPD), while accumulating evidence indicates that the activity of HDAC is decreased in lung tissue alveolar macrophages, HD...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359164/ https://www.ncbi.nlm.nih.gov/pubmed/22443498 http://dx.doi.org/10.1186/1476-9255-9-10 |