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Human telomerase RNA component (hTERC) gene amplification detected by FISH in precancerous lesions and carcinoma of the larynx

BACKGROUND: Gain of 3q26 is frequently observed in squamous cell carcinomas of mucosal origin, including those originating in the head and neck region. The human telomerase RNA component (hTERC) gene, which is located on chromosome 3q26, encodes for an RNA subunit of telomerase that maintains the le...

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Detalles Bibliográficos
Autores principales: Liu, Yu, Dong, Xiao-li, Tian, Cheng, Liu, Hong-gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359179/
https://www.ncbi.nlm.nih.gov/pubmed/22463766
http://dx.doi.org/10.1186/1746-1596-7-34