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Comparative genomics and transcriptional profiles of Saccharopolyspora erythraea NRRL 2338 and a classically improved erythromycin over-producing strain

BACKGROUND: The molecular mechanisms altered by the traditional mutation and screening approach during the improvement of antibiotic-producing microorganisms are still poorly understood although this information is essential to design rational strategies for industrial strain improvement. In this st...

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Detalles Bibliográficos
Autores principales: Peano, Clelia, Talà, Adelfia, Corti, Giorgio, Pasanisi, Daniela, Durante, Miriana, Mita, Giovanni, Bicciato, Silvio, De Bellis, Gianluca, Alifano, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359211/
https://www.ncbi.nlm.nih.gov/pubmed/22401291
http://dx.doi.org/10.1186/1475-2859-11-32