An evaluation of oligonucleotide-based therapeutic strategies for polyQ diseases

BACKGROUND: RNA interference (RNAi) and antisense strategies provide experimental therapeutic agents for numerous diseases, including polyglutamine (polyQ) disorders caused by CAG repeat expansion. We compared the potential of different oligonucleotide-based strategies for silencing the genes respon...

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Detalles Bibliográficos
Autores principales: Fiszer, Agnieszka, Olejniczak, Marta, Switonski, Pawel M, Wroblewska, Joanna P, Wisniewska-Kruk, Joanna, Mykowska, Agnieszka, Krzyzosiak, Wlodzimierz J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359213/
https://www.ncbi.nlm.nih.gov/pubmed/22397573
http://dx.doi.org/10.1186/1471-2199-13-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359213/
https://www.ncbi.nlm.nih.gov/pubmed/22397573
http://dx.doi.org/10.1186/1471-2199-13-6

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