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An evaluation of oligonucleotide-based therapeutic strategies for polyQ diseases

BACKGROUND: RNA interference (RNAi) and antisense strategies provide experimental therapeutic agents for numerous diseases, including polyglutamine (polyQ) disorders caused by CAG repeat expansion. We compared the potential of different oligonucleotide-based strategies for silencing the genes respon...

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Detalles Bibliográficos
Autores principales:	Fiszer, Agnieszka, Olejniczak, Marta, Switonski, Pawel M, Wroblewska, Joanna P, Wisniewska-Kruk, Joanna, Mykowska, Agnieszka, Krzyzosiak, Wlodzimierz J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359213/ https://www.ncbi.nlm.nih.gov/pubmed/22397573 http://dx.doi.org/10.1186/1471-2199-13-6

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