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Dual-lifetime referencing (DLR): a powerful method for on-line measurement of internal pH in carrier-bound immobilized biocatalysts

BACKGROUND: Industrial-scale biocatalytic synthesis of fine chemicals occurs preferentially as continuous processes employing immobilized enzymes on insoluble porous carriers. Diffusional effects in these systems often create substrate and product concentration gradients between bulk liquid and the...

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Detalles Bibliográficos
Autores principales: Boniello, Caterina, Mayr, Torsten, Bolivar, Juan M, Nidetzky, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359222/
https://www.ncbi.nlm.nih.gov/pubmed/22455624
http://dx.doi.org/10.1186/1472-6750-12-11