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Predicting tissue specific cis-regulatory modules in the human genome using pairs of co-occurring motifs

BACKGROUND: Researchers seeking to unlock the genetic basis of human physiology and diseases have been studying gene transcription regulation. The temporal and spatial patterns of gene expression are controlled by mainly non-coding elements known as cis-regulatory modules (CRMs) and epigenetic facto...

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Detalles Bibliográficos
Autores principales: Girgis, Hani Z, Ovcharenko, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359238/
https://www.ncbi.nlm.nih.gov/pubmed/22313678
http://dx.doi.org/10.1186/1471-2105-13-25