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DNA methylation differences at growth related genes correlate with birth weight: a molecular signature linked to developmental origins of adult disease?

BACKGROUND: Infant birth weight is a complex quantitative trait associated with both neonatal and long-term health outcomes. Numerous studies have been published in which candidate genes (IGF1, IGF2, IGF2R, IGF binding proteins, PHLDA2 and PLAGL1) have been associated with birth weight, but these st...

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Detalles Bibliográficos
Autores principales: Turan, Nahid, Ghalwash, Mohamed F, Katari, Sunita, Coutifaris, Christos, Obradovic, Zoran, Sapienza, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359247/
https://www.ncbi.nlm.nih.gov/pubmed/22498030
http://dx.doi.org/10.1186/1755-8794-5-10