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Up-regulation of hypoxia inducible factor-1α by cobalt chloride correlates with proliferation and apoptosis in PC-2 cells

BACKGROUND: The exact mechanism of the effects of hypoxia on the proliferation and apoptosis in carcinoma cells is still conflicting. This study investigated the variation of hypoxia-inducible factor-1α(HIF-1α) expression and the apoptosis effect of hypoxia stimulated by cobalt chloride (CoCl(2)) in...

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Detalles Bibliográficos
Autores principales: Dai, Zhi-Jun, Gao, Jie, Ma, Xiao-Bin, Yan, Kun, Liu, Xiao-Xu, Kang, Hua-Feng, Ji, Zong-Zheng, Guan, Hai-Tao, Wang, Xi-Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359273/
https://www.ncbi.nlm.nih.gov/pubmed/22453051
http://dx.doi.org/10.1186/1756-9966-31-28