Murine CD4(+) T Cell Responses Are Inhibited by Cytotoxic T Cell-Mediated Killing of Dendritic Cells and Are Restored by Antigen Transfer

Cytotoxic T lymphocytes (CTL) provide protection against pathogens and tumors. In addition, experiments in mouse models have shown that CTL can also kill antigen-presenting dendritic cells (DC), reducing their ability to activate primary and secondary CD8(+) T cell responses. In contrast, the effect...

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Detalles Bibliográficos
Autores principales: Ma, Joel Zhi-Iong, Lim, So Nai, Qin, Jim Shixiang, Yang, Jianping, Enomoto, Noriyuki, Ruedl, Christiane, Ronchese, Franca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359309/
https://www.ncbi.nlm.nih.gov/pubmed/22649530
http://dx.doi.org/10.1371/journal.pone.0037481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359309/
https://www.ncbi.nlm.nih.gov/pubmed/22649530
http://dx.doi.org/10.1371/journal.pone.0037481

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