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Inflammasome-Mediated IL-1β Production in Humans with Cystic Fibrosis
BACKGROUND: Inflammation and infection are major determinants of disease severity and consequently, the quality of life and outcome for patients with cystic fibrosis (CF). Interleukin-1 beta (IL-1β) is a key inflammatory mediator. Secretion of biologically active IL-1β involves inflammasome-mediated...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359311/ https://www.ncbi.nlm.nih.gov/pubmed/22649552 http://dx.doi.org/10.1371/journal.pone.0037689 |