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Common Variants in MAGI2 Gene Are Associated with Increased Risk for Cognitive Impairment in Schizophrenic Patients

Schizophrenia is a complex psychiatric disorder characterized by positive symptoms, negative symptoms, and cognitive impairment. MAGI2, a relatively large gene (∼1.5 Mbps) that maps to chromosome 7q21, is involved in recruitment of neurotransmitter receptors such as AMPA- and NMDA-type glutamate rec...

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Detalles Bibliográficos
Autores principales: Koide, Takayoshi, Banno, Masahiro, Aleksic, Branko, Yamashita, Saori, Kikuchi, Tsutomu, Kohmura, Kunihiro, Adachi, Yasunori, Kawano, Naoko, Kushima, Itaru, Nakamura, Yukako, Okada, Takashi, Ikeda, Masashi, Ohi, Kazutaka, Yasuda, Yuka, Hashimoto, Ryota, Inada, Toshiya, Ujike, Hiroshi, Iidaka, Tetsuya, Suzuki, Michio, Takeda, Masatoshi, Iwata, Nakao, Ozaki, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359314/
https://www.ncbi.nlm.nih.gov/pubmed/22649501
http://dx.doi.org/10.1371/journal.pone.0036836