NKT Cells Stimulated by Long Fatty Acyl Chain Sulfatides Significantly Reduces the Incidence of Type 1 Diabetes in Nonobese Diabetic Mice

Sulfatide-reactive type II NKT cells have been shown to regulate autoimmunity and anti-tumor immunity. Although, two major isoforms of sulfatide, C16:0 and C24:0, are enriched in the pancreas, their relative role in autoimmune diabetes is not known. Here, we report that sulfatide/CD1d-tetramer(+) ce...

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Detalles Bibliográficos
Autores principales: Subramanian, Lakshmimathy, Blumenfeld, Hartley, Tohn, Robert, Ly, Dalam, Aguilera, Carlos, Maricic, Igor, Mansson, Jan-Eric, Buschard, Karsten, Kumar, Vipin, Delovitch, Terry L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359325/
https://www.ncbi.nlm.nih.gov/pubmed/22649557
http://dx.doi.org/10.1371/journal.pone.0037771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359325/
https://www.ncbi.nlm.nih.gov/pubmed/22649557
http://dx.doi.org/10.1371/journal.pone.0037771

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