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Effect of Chromosomal Instability on the Mutation-Selection Balance in Unicellular Populations

This paper develops a mathematical model describing the evolutionary dynamics of a unicellular, asexually replicating population exhibiting chromosomal instability. Chromosomal instability is a form of genetic instability characterized by the gain or loss of entire chromosomes during cell division....

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Detalles Bibliográficos
Autores principales: Itan, Eran, Tannenbaum, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359333/
https://www.ncbi.nlm.nih.gov/pubmed/22649487
http://dx.doi.org/10.1371/journal.pone.0026513