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Effect of Chromosomal Instability on the Mutation-Selection Balance in Unicellular Populations
This paper develops a mathematical model describing the evolutionary dynamics of a unicellular, asexually replicating population exhibiting chromosomal instability. Chromosomal instability is a form of genetic instability characterized by the gain or loss of entire chromosomes during cell division....
Autores principales: | Itan, Eran, Tannenbaum, Emmanuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359333/ https://www.ncbi.nlm.nih.gov/pubmed/22649487 http://dx.doi.org/10.1371/journal.pone.0026513 |
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