A Predictive Model of Intein Insertion Site for Use in the Engineering of Molecular Switches

Inteins are intervening protein domains with self-splicing ability that can be used as molecular switches to control activity of their host protein. Successfully engineering an intein into a host protein requires identifying an insertion site that permits intein insertion and splicing while allowing...

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Detalles Bibliográficos
Autores principales: Apgar, James, Ross, Mary, Zuo, Xiao, Dohle, Sarah, Sturtevant, Derek, Shen, Binzhang, de la Vega, Humberto, Lessard, Philip, Lazar, Gabor, Raab, R. Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359363/
https://www.ncbi.nlm.nih.gov/pubmed/22649521
http://dx.doi.org/10.1371/journal.pone.0037355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359363/
https://www.ncbi.nlm.nih.gov/pubmed/22649521
http://dx.doi.org/10.1371/journal.pone.0037355

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