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DNA promoter methylation status and protein expression of interleukin-8 in human colorectal adenocarcinomas

BACKGROUND: Interleukin-8 (IL-8) also referred to as CXCL8, a member of the CXC chemokine family that attracts neutrophils and other leukocytes, has been associated with cancer. Angiogenesis is a prime regulator of tumour expansion and data support that IL-8 is a potent angiogenic factor. Epigenomic...

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Detalles Bibliográficos
Autores principales: Dimberg, Jan, Ström, Karin, Löfgren, Sture, Zar, Niklas, Lindh, Mikael, Matussek, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359445/
https://www.ncbi.nlm.nih.gov/pubmed/22108905
http://dx.doi.org/10.1007/s00384-011-1367-5