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The formation of complex acetylcholine receptor clusters requires MuSK kinase activity and structural information from the MuSK extracellular domain

Efficient synaptic transmission at the neuromuscular junction (NMJ) requires the topological maturation of the postsynaptic apparatus from an oval acetylcholine receptor (AChR)-rich plaque into a complex pretzel-shaped array of branches. However, compared to NMJ formation very little is known about...

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Detalles Bibliográficos
Autores principales: Mazhar, Sania, Herbst, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359500/
https://www.ncbi.nlm.nih.gov/pubmed/22210232
http://dx.doi.org/10.1016/j.mcn.2011.12.007