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FK228 Analogues Induce Fetal Hemoglobin in Human Erythroid Progenitors

Fetal hemoglobin (HbF) improves the clinical severity of sickle cell disease (SCD), therefore, research to identify HbF-inducing agents for treatment purposes is desirable. The focus of our study is to investigate the ability of FK228 analogues to induce HbF using a novel KU812 dual-luciferase repor...

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Detalles Bibliográficos
Autores principales: Makala, Levi, Di Maro, Salvatore, Lou, Tzu-Fang, Sivanand, Sharanya, Ahn, Jung-Mo, Pace, Betty S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359661/
https://www.ncbi.nlm.nih.gov/pubmed/22655179
http://dx.doi.org/10.1155/2012/428137