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S-Glutathionylation of Protein Disulfide Isomerase Regulates Estrogen Receptor α Stability and Function

S-Glutathionylation of cysteine residues within target proteins is a posttranslational modification that alters structure and function. We have shown that S-glutathionylation of protein disulfide isomerase (PDI) disrupts protein folding and leads to the activation of the unfolded protein response (U...

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Detalles Bibliográficos
Autores principales: Xiong, Ying, Manevich, Yefim, Tew, Kenneth D., Townsend, Danyelle M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Journal of Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359683/
https://www.ncbi.nlm.nih.gov/pubmed/22654912
http://dx.doi.org/10.1155/2012/273549