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Inference of Tumor Phylogenies from Genomic Assays on Heterogeneous Samples

Tumorigenesis can in principle result from many combinations of mutations, but only a few roughly equivalent sequences of mutations, or “progression pathways,” seem to account for most human tumors. Phylogenetics provides a promising way to identify common progression pathways and markers of those p...

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Detalles Bibliográficos
Autores principales: Subramanian, Ayshwarya, Shackney, Stanley, Schwartz, Russell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359715/
https://www.ncbi.nlm.nih.gov/pubmed/22654484
http://dx.doi.org/10.1155/2012/797812