Cargando…

Global Gene Expression Profiling in PPAR-γ Agonist-Treated Kidneys in an Orthologous Rat Model of Human Autosomal Recessive Polycystic Kidney Disease

Kidneys are enlarged by aberrant proliferation of tubule epithelial cells leading to the formation of numerous cysts, nephron loss, and interstitial fibrosis in polycystic kidney disease (PKD). Pioglitazone (PIO), a PPAR-γ agonist, decreased cell proliferation, interstitial fibrosis, and inflammatio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yoshihara, Daisuke, Kugita, Masanori, Yamaguchi, Tamio, Aukema, Harold M., Kurahashi, Hiroki, Morita, Miwa, Hiki, Yoshiyuki, Calvet, James P., Wallace, Darren P., Toyohara, Takafumi, Abe, Takaaki, Nagao, Shizuko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359747/ https://www.ncbi.nlm.nih.gov/pubmed/22666229 http://dx.doi.org/10.1155/2012/695898

Ejemplares similares

Telmisartan Ameliorates Fibrocystic Liver Disease in an Orthologous Rat Model of Human Autosomal Recessive Polycystic Kidney Disease
por: Yoshihara, Daisuke, et al.
Publicado: (2013)

Beneficial effect of combined treatment with octreotide and pasireotide in PCK rats, an orthologous model of human autosomal recessive polycystic kidney disease
por: Kugita, Masanori, et al.
Publicado: (2017)

Mitochondrial Abnormality Facilitates Cyst Formation in Autosomal Dominant Polycystic Kidney Disease
por: Ishimoto, Yu, et al.
Publicado: (2017)

Autosomal Recessive Polycystic Kidney Disease
por: Salati, Sajad Ahmad
Publicado: (2014)

Autosomal Recessive Polycystic Kidney Disease
por: Hafer, Ashley S., et al.
Publicado: (2017)

Review of the Use of Animal Models of Human Polycystic Kidney Disease for the Evaluation of Experimental Therapeutic Modalities
por: Nagao, Shizuko, et al.
Publicado: (2023)

Increased salt intake does not worsen the progression of renal cystic disease in high water-loaded PCK rats
por: Nagao, Shizuko, et al.
Publicado: (2019)

Lack of Benefit of Early Intervention with Dietary Flax and Fish Oil and Soy Protein in Orthologous Rodent Models of Human Hereditary Polycystic Kidney Disease
por: Yamaguchi, Tamio, et al.
Publicado: (2016)

Intragenic duplication in the PHKD1 gene in autosomal recessive polycystic kidney disease
por: Miyazaki, Jun, et al.
Publicado: (2015)

Autosomal recessive polycystic kidney disease diagnosed in fetus
por: Thomas, Joseph, et al.
Publicado: (2007)

Molecular Pathophysiology of Autosomal Recessive Polycystic Kidney Disease
por: Cordido, Adrian, et al.
Publicado: (2021)

Early clinical management of autosomal recessive polycystic kidney disease
por: Liebau, Max Christoph
Publicado: (2021)

Phenotypic Variability in Siblings With Autosomal Recessive Polycystic Kidney Disease
por: Ajiri, Ramona, et al.
Publicado: (2022)

Fatal outcome of autosomal recessive polycystic kidney disease in neonates with recessive PKHD1 mutations
por: Jung, Jiwon, et al.
Publicado: (2020)

Autosomal dominant and autosomal recessive polycystic kidney disease: hypertension and secondary cardiovascular effect in children
por: Lucchetti, L., et al.
Publicado: (2023)

Atypical Clinical Presentation of Autosomal Recessive Polycystic Kidney Mimicking Medullary Sponge Kidney Disease
por: Letavernier, Emmanuel, et al.
Publicado: (2021)

Autosomal Recessive Polycystic Kidney Disease: Antenatal Diagnosis and Histopathological Correlation
por: Rajanna, Dayananda Kumar, et al.
Publicado: (2013)

Genetics of Autosomal Recessive Polycystic Kidney Disease and Its Differential Diagnoses
por: Bergmann, Carsten
Publicado: (2018)

Extracranial Aneurysms in 2 Patients with Autosomal Recessive Polycystic Kidney Disease
por: Elchediak, Daniel S., et al.
Publicado: (2017)

Diagnosis and Management of Hepatobiliary Complications in Autosomal Recessive Polycystic Kidney Disease
por: Wehrman, Andrew, et al.
Publicado: (2017)

Clinical and genetic characteristics of autosomal recessive polycystic kidney disease in Oman
por: Al Alawi, Intisar, et al.
Publicado: (2020)

Multiple Cerebral Aneurysms in an Adult With Autosomal Recessive Polycystic Kidney Disease
por: Gately, Ryan, et al.
Publicado: (2020)

Therapeutic Potential for CFTR Correctors in Autosomal Recessive Polycystic Kidney Disease
por: Yanda, Murali K., et al.
Publicado: (2021)

Tesevatinib ameliorates progression of polycystic kidney disease in rodent models of autosomal recessive polycystic kidney disease
por: Sweeney, William E, et al.
Publicado: (2017)

Kidney concentrating capacity in children with autosomal recessive polycystic kidney disease is linked to glomerular filtration and hypertension
por: Seeman, Tomáš, et al.
Publicado: (2022)

Risk Factors for Neurocognitive Functioning in Children with Autosomal Recessive Polycystic Kidney Disease
por: Hooper, Stephen R.
Publicado: (2017)

Fatty Acid Oxidation is Impaired in An Orthologous Mouse Model of Autosomal Dominant Polycystic Kidney Disease
por: Menezes, Luis F., et al.
Publicado: (2016)

Pulmonary hypertension in a child with juvenile-type autosomal recessive polycystic kidney disease.
por: Huh, J., et al.
Publicado: (1999)

Growth in Children with Autosomal Recessive Polycystic Kidney Disease in the CKiD Cohort Study
por: Hartung, Erum A., et al.
Publicado: (2016)

Transient Elastography for Detection of Liver Fibrosis in Children With Autosomal Recessive Polycystic Kidney Disease
por: Wicher, Dorota, et al.
Publicado: (2019)

Recent Progress of the ARegPKD Registry Study on Autosomal Recessive Polycystic Kidney Disease
por: Ebner, Kathrin, et al.
Publicado: (2017)

Clinical courses and complications of young adults with Autosomal Recessive Polycystic Kidney Disease (ARPKD)
por: Burgmaier, Kathrin, et al.
Publicado: (2019)

Clinical Characteristics and Courses of Patients With Autosomal Recessive Polycystic Kidney Disease-Mimicking Phenocopies
por: Halawi, Abdul A., et al.
Publicado: (2023)

Effect of calcium-sensing receptor activation in models of autosomal recessive or dominant polycystic kidney disease
por: Wang, Xiaofang, et al.
Publicado: (2009)

Caroli's Syndrome with Autosomal Recessive Polycystic Kidney Disease in a Two Month Old Infant
por: Kim, Jeong Tae, et al.
Publicado: (2006)

Improved Structure and Function in Autosomal Recessive Polycystic Rat Kidneys with Renal Tubular Cell Therapy
por: Kelly, K. J., et al.
Publicado: (2015)

Evidence for a “Pathogenic Triumvirate” in Congenital Hepatic Fibrosis in Autosomal Recessive Polycystic Kidney Disease
por: Jiang, Lu, et al.
Publicado: (2016)

Prenatal MR imaging features of Caroli syndrome in association with autosomal recessive polycystic kidney disease
por: Rivas, Amanda, et al.
Publicado: (2018)

Autosomal recessive polycystic kidney disease (ARPKD) in a Nigerian newborn: a case report
por: Bolaji, Olufunke, et al.
Publicado: (2018)

A Potential Therapy Using Antisense Oligonucleotides to Treat Autosomal Recessive Polycystic Kidney Disease
por: Li, Huixia, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ovij9lbpphoeujhqn35hjhc0m9