Functional identification of pathogenic autoantibody responses in patients with multiple sclerosis

Pathological and clinical studies implicate antibody-dependent mechanisms in the immunopathogenesis of multiple sclerosis. We tested this hypothesis directly by investigating the ability of patient-derived immunoglobulins to mediate demyelination and axonal injury in vitro. Using a myelinating cultu...

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Detalles Bibliográficos
Autores principales: Elliott, Christina, Lindner, Maren, Arthur, Ariel, Brennan, Kathryn, Jarius, Sven, Hussey, John, Chan, Andrew, Stroet, Anke, Olsson, Tomas, Willison, Hugh, Barnett, Susan C., Meinl, Edgar, Linington, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359756/
https://www.ncbi.nlm.nih.gov/pubmed/22561643
http://dx.doi.org/10.1093/brain/aws105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359756/
https://www.ncbi.nlm.nih.gov/pubmed/22561643
http://dx.doi.org/10.1093/brain/aws105

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