Cargando…
Therapeutic targeting of epidermal growth factor receptor in human cancer: successes and limitations
Epidermal growth factor receptor (EGFR) is one of the most commonly altered genes in human cancer by way of over-expression, amplification, and mutation. Targeted inhibition of EGFR activity suppresses signal transduction pathways which control tumor cell growth, proliferation, and resistance to apo...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sun Yat-sen University Cancer Center
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359794/ https://www.ncbi.nlm.nih.gov/pubmed/21192840 http://dx.doi.org/10.5732/cjc.010.10542 |