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Therapeutic targeting of epidermal growth factor receptor in human cancer: successes and limitations

Epidermal growth factor receptor (EGFR) is one of the most commonly altered genes in human cancer by way of over-expression, amplification, and mutation. Targeted inhibition of EGFR activity suppresses signal transduction pathways which control tumor cell growth, proliferation, and resistance to apo...

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Detalles Bibliográficos
Autores principales:	Wykosky, Jill, Fenton, Tim, Furnari, Frank, Cavenee, Webster K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sun Yat-sen University Cancer Center 2011
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359794/ https://www.ncbi.nlm.nih.gov/pubmed/21192840 http://dx.doi.org/10.5732/cjc.010.10542

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