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Essential role for telomerase in chronic myeloid leukemia induced by BCR-ABL in mice

The telomerase protein is constitutively activated in malignant cells from many patients with cancer, including the chronic myeloid leukemia (CML), but whether telomerase is essential for the pathogenesis of this disease is not known. Here, we used telomerase deficient mice to determine the requirem...

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Detalles Bibliográficos
Autores principales: Vicente-Dueñas, Carolina, Barajas-Diego, Marcos, Romero-Camarero, Isabel, González-Herrero, Inés, Flores, Teresa, Sánchez-García, Isidro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359883/
https://www.ncbi.nlm.nih.gov/pubmed/22408137