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Essential role for telomerase in chronic myeloid leukemia induced by BCR-ABL in mice
The telomerase protein is constitutively activated in malignant cells from many patients with cancer, including the chronic myeloid leukemia (CML), but whether telomerase is essential for the pathogenesis of this disease is not known. Here, we used telomerase deficient mice to determine the requirem...
Autores principales: | Vicente-Dueñas, Carolina, Barajas-Diego, Marcos, Romero-Camarero, Isabel, González-Herrero, Inés, Flores, Teresa, Sánchez-García, Isidro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359883/ https://www.ncbi.nlm.nih.gov/pubmed/22408137 |
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