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Over-expression of Thioredoxin-1 mediates growth, survival, and chemoresistance and is a druggable target in diffuse large B-cell lymphoma

Diffuse Large B cell lymphomas (DLBCL) are the most prevalent of the non-Hodgkin lymphomas and are currently initially treated fairly successfully, but frequently relapse as refractory disease, resulting in poor salvage therapy options and short survival. The greatest challenge in improving survival...

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Detalles Bibliográficos
Autores principales: Li, Changping, Thompson, Michael A., Tamayo, Archito T., Zuo, Zhuang, Lee, John, Vega, Francisco, Ford, Richard J., Pham, Lan V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359887/
https://www.ncbi.nlm.nih.gov/pubmed/22447839