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A Two-Dimensional Model of the Colonic Crypt Accounting for the Role of the Basement Membrane and Pericryptal Fibroblast Sheath

The role of the basement membrane is vital in maintaining the integrity and structure of an epithelial layer, acting as both a mechanical support and forming the physical interface between epithelial cells and the surrounding connective tissue. The function of this membrane is explored here in the c...

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Detalles Bibliográficos
Autores principales: Dunn, Sara-Jane, Appleton, Paul L., Nelson, Scott A., Näthke, Inke S., Gavaghan, David J., Osborne, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359972/
https://www.ncbi.nlm.nih.gov/pubmed/22654652
http://dx.doi.org/10.1371/journal.pcbi.1002515