A Duplication CNV That Conveys Traits Reciprocal to Metabolic Syndrome and Protects against Diet-Induced Obesity in Mice and Men

The functional contribution of CNV to human biology and disease pathophysiology has undergone limited exploration. Recent observations in humans indicate a tentative link between CNV and weight regulation. Smith-Magenis syndrome (SMS), manifesting obesity and hypercholesterolemia, results from a del...

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Detalles Bibliográficos
Autores principales: Lacaria, Melanie, Saha, Pradip, Potocki, Lorraine, Bi, Weimin, Yan, Jiong, Girirajan, Santhosh, Burns, Brooke, Elsea, Sarah, Walz, Katherina, Chan, Lawrence, Lupski, James R., Gu, Wenli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359973/
https://www.ncbi.nlm.nih.gov/pubmed/22654670
http://dx.doi.org/10.1371/journal.pgen.1002713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359973/
https://www.ncbi.nlm.nih.gov/pubmed/22654670
http://dx.doi.org/10.1371/journal.pgen.1002713

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