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IL-12 and GM-CSF in DNA/MVA Immunizations against HIV-1 CRF12_BF Nef Induced T-Cell Responses With an Enhanced Magnitude, Breadth and Quality

In Argentina, the HIV epidemic is characterized by the co-circulation of subtype B and BF recombinant viral variants. Nef is an HIV protein highly variable among subtypes, making it a good tool to study the impact of HIV variability in the vaccine design setting. We have previously reported a specif...

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Detalles Bibliográficos
Autores principales: Rodríguez, Ana María, Pascutti, María Fernanda, Maeto, Cynthia, Falivene, Juliana, Holgado, María Pía, Turk, Gabriela, Gherardi, María Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360004/
https://www.ncbi.nlm.nih.gov/pubmed/22655069
http://dx.doi.org/10.1371/journal.pone.0037801