Improved Somatic Mutagenesis in Zebrafish Using Transcription Activator-Like Effector Nucleases (TALENs)

Zinc Finger Nucleases (ZFNs) made by Context-Dependent Assembly (CoDA) and Transcription Activator-Like Effector Nucleases (TALENs) provide robust and user-friendly technologies for efficiently inactivating genes in zebrafish. These designer nucleases bind to and cleave DNA at particular target site...

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Detalles Bibliográficos
Autores principales: Moore, Finola E., Reyon, Deepak, Sander, Jeffry D., Martinez, Sarah A., Blackburn, Jessica S., Khayter, Cyd, Ramirez, Cherie L., Joung, J. Keith, Langenau, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360007/
https://www.ncbi.nlm.nih.gov/pubmed/22655075
http://dx.doi.org/10.1371/journal.pone.0037877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360007/
https://www.ncbi.nlm.nih.gov/pubmed/22655075
http://dx.doi.org/10.1371/journal.pone.0037877

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