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Combination of RGD Compound and Low-Dose Paclitaxel Induces Apoptosis in Human Glioblastoma Cells

BACKGROUND: Integrins are a family of transmembrane adhesion proteins that mediate cell adhesion and intracellular signaling. Integrin-αvβ3 is expressed on the surface of human glioblastoma cells, and can be further induced by chemical stress. The Arg-Gly-Asp (RGD) motif-containing peptides are spec...

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Detalles Bibliográficos
Autores principales: Chang, Ming-Wei, Lo, Jem-Mau, Juan, Hsueh-Fen, Chang, Hsin-Yi, Chuang, Chun-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360022/
https://www.ncbi.nlm.nih.gov/pubmed/22655084
http://dx.doi.org/10.1371/journal.pone.0037935