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Identification of Sare0718 As an Alanine-Activating Adenylation Domain in Marine Actinomycete Salinispora arenicola CNS-205

BACKGROUND: Amino acid adenylation domains (A domains) are critical enzymes that dictate the identity of the amino acid building blocks to be incorporated during nonribosomal peptide (NRP) biosynthesis. NRPs represent a large group of valuable natural products that are widely applied in medicine, ag...

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Detalles Bibliográficos
Autores principales: Xia, Sisi, Ma, Yanlin, Zhang, Wei, Yang, Yi, Wu, Shaowen, Zhu, Minzhe, Deng, Lingfu, Li, Bing, Liu, Zhonglai, Qi, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360062/
https://www.ncbi.nlm.nih.gov/pubmed/22655051
http://dx.doi.org/10.1371/journal.pone.0037487