Identification of Novel Liver X Receptor Activators by Structure-Based Modeling

[Image: see text] Liver X receptors (LXRs) are members of the nuclear receptor family. Activators of LXRs are of high pharmacological interest as LXRs regulate cholesterol, fatty acid, and carbohydrate metabolism as well as inflammatory processes. On the basis of different X-ray crystal structures,...

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Detalles Bibliográficos
Autores principales: von Grafenstein, Susanne, Mihaly-Bison, Judit, Wolber, Gerhard, Bochkov, Valery N., Liedl, Klaus R., Schuster, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360526/
https://www.ncbi.nlm.nih.gov/pubmed/22489742
http://dx.doi.org/10.1021/ci300096c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360526/
https://www.ncbi.nlm.nih.gov/pubmed/22489742
http://dx.doi.org/10.1021/ci300096c

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