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Identification of Novel Liver X Receptor Activators by Structure-Based Modeling
[Image: see text] Liver X receptors (LXRs) are members of the nuclear receptor family. Activators of LXRs are of high pharmacological interest as LXRs regulate cholesterol, fatty acid, and carbohydrate metabolism as well as inflammatory processes. On the basis of different X-ray crystal structures,...
Autores principales: | von Grafenstein, Susanne, Mihaly-Bison, Judit, Wolber, Gerhard, Bochkov, Valery N., Liedl, Klaus R., Schuster, Daniela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360526/ https://www.ncbi.nlm.nih.gov/pubmed/22489742 http://dx.doi.org/10.1021/ci300096c |
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