Lipoxin A(4) Stimulates Calcium-Activated Chloride Currents and Increases Airway Surface Liquid Height in Normal and Cystic Fibrosis Airway Epithelia

Cystic Fibrosis (CF) is a genetic disease characterised by a deficit in epithelial Cl(−) secretion which in the lung leads to airway dehydration and a reduced Airway Surface Liquid (ASL) height. The endogenous lipoxin LXA(4) is a member of the newly identified eicosanoids playing a key role in endin...

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Detalles Bibliográficos
Autores principales: Verrière, Valia, Higgins, Gerard, Al-Alawi, Mazen, Costello, Richard W., McNally, Paul, Chiron, Raphaël, Harvey, Brian J., Urbach, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360607/
https://www.ncbi.nlm.nih.gov/pubmed/22662206
http://dx.doi.org/10.1371/journal.pone.0037746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360607/
https://www.ncbi.nlm.nih.gov/pubmed/22662206
http://dx.doi.org/10.1371/journal.pone.0037746

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