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Lipoxin A(4) Stimulates Calcium-Activated Chloride Currents and Increases Airway Surface Liquid Height in Normal and Cystic Fibrosis Airway Epithelia
Cystic Fibrosis (CF) is a genetic disease characterised by a deficit in epithelial Cl(−) secretion which in the lung leads to airway dehydration and a reduced Airway Surface Liquid (ASL) height. The endogenous lipoxin LXA(4) is a member of the newly identified eicosanoids playing a key role in endin...
Autores principales: | Verrière, Valia, Higgins, Gerard, Al-Alawi, Mazen, Costello, Richard W., McNally, Paul, Chiron, Raphaël, Harvey, Brian J., Urbach, Valérie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360607/ https://www.ncbi.nlm.nih.gov/pubmed/22662206 http://dx.doi.org/10.1371/journal.pone.0037746 |
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