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Hyaluronan Binding Motifs of USP17 and SDS3 Exhibit Anti-Tumor Activity
BACKGROUND: We previously reported that the USP17 deubiquitinating enzyme having hyaluronan binding motifs (HABMs) interacts with human SDS3 (suppressor of defective silencing 3) and specifically deubiquitinates Lys-63 branched polyubiquitination of SDS3 resulting in negative regulation of histone d...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360616/ https://www.ncbi.nlm.nih.gov/pubmed/22662218 http://dx.doi.org/10.1371/journal.pone.0037772 |