Mechanism Underlying Defective Interferon Gamma-Induced IDO Expression in Non-obese Diabetic Mouse Fibroblasts

Indoleamine 2,3-dioxygenase (IDO) can locally suppress T cell-mediated immune responses. It has been shown that defective self-tolerance in early prediabetic female non-obese diabetic (NOD) mice can be attributed to the impaired interferon-gamma (IFN-γ)- induced IDO expression in dendritic cells of...

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Detalles Bibliográficos
Autores principales: Hosseini-Tabatabaei, Azadeh, Jalili, Reza Baradar, Li, Yunyuan, Kilani, Ruhangiz T., Moeen Rezakhanlou, Alireza, Ghahary, Aziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360620/
https://www.ncbi.nlm.nih.gov/pubmed/22662207
http://dx.doi.org/10.1371/journal.pone.0037747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360620/
https://www.ncbi.nlm.nih.gov/pubmed/22662207
http://dx.doi.org/10.1371/journal.pone.0037747

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