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Low Dose Vaccination with Attenuated Francisella tularensis Strain SchuS4 Mutants Protects against Tularemia Independent of the Route of Vaccination

Tularemia, caused by the Gram-negative bacterium Francisella tularensis, is a severe, sometimes fatal disease. Interest in tularemia has increased over the last decade due to its history as a biological weapon. In particular, development of novel vaccines directed at protecting against pneumonic tul...

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Detalles Bibliográficos
Autores principales: Rockx-Brouwer, Dedeke, Chong, Audrey, Wehrly, Tara D., Child, Robert, Crane, Deborah D., Celli, Jean, Bosio, Catharine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360632/
https://www.ncbi.nlm.nih.gov/pubmed/22662210
http://dx.doi.org/10.1371/journal.pone.0037752