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Identification and Function of Exchange Proteins Activated Directly by Cyclic AMP (Epac) in Mammalian Spermatozoa

The role of cAMP in spermatic functions was classically thought to be mediated exclusively through the activation of Protein Kinase A (PKA). However, it has recently been shown that cAMP also exerts its effects through a PKA-independent pathway activating a family of proteins known as Epac proteins....

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Detalles Bibliográficos
Autores principales: Miro-Moran, Alvaro, Jardin, Isaac, Ortega-Ferrusola, Cristina, Salido, Gines M., Peña, Fernando J., Tapia, Jose A., Aparicio, Ines M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360633/
https://www.ncbi.nlm.nih.gov/pubmed/22662198
http://dx.doi.org/10.1371/journal.pone.0037713