The KRAS-Variant Is Associated with Risk of Developing Double Primary Breast and Ovarian Cancer

PURPOSE: A germline microRNA binding site-disrupting variant, the KRAS-variant (rs61764370), is associated with an increased risk of developing several cancers. Because this variant is most strongly associated with ovarian cancer risk in patients from hereditary breast and ovarian families (HBOC), a...

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Detalles Bibliográficos
Autores principales: Pilarski, Robert, Patel, Divya A., Weitzel, Jeffrey, McVeigh, Terri, Dorairaj, Jemima J., Heneghan, Helen M., Miller, Nicola, Weidhaas, Joanne B., Kerin, Michael J., McKenna, Megan, Wu, Xifeng, Hildebrandt, Michelle, Zelterman, Daniel, Sand, Sharon, Shulman, Lee P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360659/
https://www.ncbi.nlm.nih.gov/pubmed/22662244
http://dx.doi.org/10.1371/journal.pone.0037891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360659/
https://www.ncbi.nlm.nih.gov/pubmed/22662244
http://dx.doi.org/10.1371/journal.pone.0037891

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