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Topical Insulin Accelerates Wound Healing in Diabetes by Enhancing the AKT and ERK Pathways: A Double-Blind Placebo-Controlled Clinical Trial

BACKGROUND: Wound healing is impaired in diabetes mellitus, but the mechanisms involved in this process are virtually unknown. Proteins belonging to the insulin signaling pathway respond to insulin in the skin of rats. OBJECTIVE: The purpose of this study was to investigate the regulation of the ins...

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Detalles Bibliográficos
Autores principales: Lima, Maria H. M., Caricilli, Andréa M., de Abreu, Lélia L., Araújo, Eliana P., Pelegrinelli, Fabiana F., Thirone, Ana C. P., Tsukumo, Daniela M., Pessoa, Ana Flávia M., dos Santos, Marinilce F., de Moraes, Maria A., Carvalheira, José B. C., Velloso, Lício A., Saad, Mario J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360697/
https://www.ncbi.nlm.nih.gov/pubmed/22662132
http://dx.doi.org/10.1371/journal.pone.0036974