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Topical Insulin Accelerates Wound Healing in Diabetes by Enhancing the AKT and ERK Pathways: A Double-Blind Placebo-Controlled Clinical Trial
BACKGROUND: Wound healing is impaired in diabetes mellitus, but the mechanisms involved in this process are virtually unknown. Proteins belonging to the insulin signaling pathway respond to insulin in the skin of rats. OBJECTIVE: The purpose of this study was to investigate the regulation of the ins...
Autores principales: | Lima, Maria H. M., Caricilli, Andréa M., de Abreu, Lélia L., Araújo, Eliana P., Pelegrinelli, Fabiana F., Thirone, Ana C. P., Tsukumo, Daniela M., Pessoa, Ana Flávia M., dos Santos, Marinilce F., de Moraes, Maria A., Carvalheira, José B. C., Velloso, Lício A., Saad, Mario J. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360697/ https://www.ncbi.nlm.nih.gov/pubmed/22662132 http://dx.doi.org/10.1371/journal.pone.0036974 |
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