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Central Role of SREBP-2 in the Pathogenesis of Osteoarthritis

BACKGROUND: Recent studies have implied that osteoarthritis (OA) is a metabolic disease linked to deregulation of genes involved in lipid metabolism and cholesterol efflux. Sterol Regulatory Element Binding Proteins (SREBPs) are transcription factors regulating lipid metabolism with so far no associ...

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Detalles Bibliográficos
Autores principales: Kostopoulou, Fotini, Gkretsi, Vasiliki, Malizos, Konstantinos N., Iliopoulos, Dimitrios, Oikonomou, Pagona, Poultsides, Lazaros, Tsezou, Aspasia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360703/
https://www.ncbi.nlm.nih.gov/pubmed/22662110
http://dx.doi.org/10.1371/journal.pone.0035753